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RCT

Randomized Controlled Trial

RCT (Randomized Controlled Trial) is considered the gold standard of scientific research. In an RCT, participants are randomly assigned to either receive an intervention (like a specific diet or medication) or a control condition, allowing researchers to establish cause-and-effect relationships more reliably than observational studies. Random assignment helps eliminate bias and ensures the groups are comparable. However, RCTs aren't perfect—they can be expensive, short-term, and difficult to conduct for dietary interventions where people need to change their eating habits for months or years. When evaluating nutrition research, RCTs provide stronger evidence than observational studies, but even RCTs can have limitations in design, funding sources, and how results are interpreted.

  Research (4)

A food-based, low-energy, low-carbohydrate diet for people with type 2 diabetes in primary care: A randomized controlled feasibility trial

Elizabeth Morris, Paul Aveyard, Pamela Dyson, Michaela Noreik, Clare Bailey, Robin Fox, Derek Jerome, Garry D Tan, Susan A Jebb

Diabetes, Obesity and Metabolism 2020

A nurse‑delivered, real‑food low‑energy, low‑carb plan led to far greater weight loss and HbA1c reductions in 12 weeks than usual care. Short‑term cardiometabolic markers and medication use improved too.

Effects of a low carbohydrate diet on energy expenditure during weight loss maintenance: randomized trial

C B Ebbeling, H A Feldman, G L Klein, J M Wong, L Bielak, S K Steltz, P K Luoto, R R Wolfe, W W Wong, D S Ludwig

BMJ (Clinical research ed.) 2018

Tired of regaining weight after dieting? Research shows that a low-carb diet significantly boosts your daily calorie burn—up to 478 calories for those with high insulin secretion—making long-term weight maintenance dramatically easier.

Effects of a low-carbohydrate diet in adults with type 1 diabetes management: A single arm non-randomised clinical trial

Jessica L Turton, Grant D Brinkworth, Helen M Parker, David Lim, Kevin Lee, Amy Rush, Rebecca Johnson, Kieron B Rooney

PLOS ONE 2023

Low‑carb, dietitian‑guided eating in type 1 diabetes improved HbA1c, time‑in‑range, and cut insulin—without more hypos or ketoacidosis. Short‑term, promising, needs larger trials.